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Hervé Boutin Selected Research

PK 11195 (PK11195)

12/2021TSPO imaging in animal models of brain diseases.
1/2013[18F]DPA-714: direct comparison with [11C]PK11195 in a model of cerebral ischemia in rats.
5/2010In vivo imaging of neuroinflammation: a comparative study between [(18)F]PBR111, [ (11)C]CLINME and [ (11)C]PK11195 in an acute rodent model.
12/2008Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers.
11/2007In vivo imaging of brain lesions with [(11)C]CLINME, a new PET radioligand of peripheral benzodiazepine receptors.
4/200711C-DPA-713: a novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation.

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Hervé Boutin Research Topics

Disease

14Neuroinflammatory Diseases
12/2021 - 04/2007
4Alzheimer Disease (Alzheimer's Disease)
03/2022 - 07/2017
4Stroke (Strokes)
12/2021 - 11/2007
3Inflammation (Inflammations)
01/2017 - 05/2010
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2020 - 04/2007
2Brain Diseases (Brain Disorder)
01/2013 - 12/2008
2Brain Ischemia (Cerebral Ischemia)
01/2013 - 06/2003
2Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
11/2007 - 06/2003
1Dehydration (Water Stress)
03/2022
1Gliosis
01/2020
1Cognitive Dysfunction
01/2020
1Mucopolysaccharidoses
01/2020
1Infections
01/2018
1Dementia (Dementias)
01/2018
1Amyloid Plaque
01/2018
1Pathologic Processes
01/2017
1Nervous System Diseases (Neurological Disorders)
05/2010
1Infarction (Infarctions)
11/2007

Drug/Important Bio-Agent (IBA)

8Proteins (Proteins, Gene)FDA Link
12/2021 - 12/2008
6PK 11195 (PK11195)IBA
12/2021 - 04/2007
6Biomarkers (Surrogate Marker)IBA
12/2021 - 11/2007
5GABA-A Receptors (GABA(A) Receptor)IBA
05/2010 - 04/2007
4(R)- (11C)1- (2- chlorophenyl)- N- methyl- N- (1- methylpropyl)- 3- isoquinolinecarboxamideIBA
12/2021 - 12/2008
3N,N- diethyl- 2- (2- (4- (2- fluoroethoxy)phenyl)- 5,7- dimethylpyrazolo(1,5- a)pyrimidin- 3- yl)acetamideIBA
01/2021 - 01/2013
3LigandsIBA
01/2013 - 04/2007
2Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
01/2020 - 11/2010
2Pharmaceutical PreparationsIBA
01/2018 - 12/2008
22- (6- chloro- 2- (4- iodophenyl)- imidazo(1,2- alpha)pyridin- 3- yl)- N- ethyl- N- methyl- acetamideIBA
05/2010 - 11/2007
2acetamideIBA
03/2009 - 04/2007
2kappa Opioid Receptors (kappa Opioid Receptor)IBA
11/2007 - 06/2003
2Opioid Receptors (Opioid Receptor)IBA
11/2007 - 06/2003
1Amyloid (Amyloid Fibrils)IBA
03/2022
1Ethanol (Ethyl Alcohol)IBA
03/2022
1PrionsIBA
03/2022
1LipopolysaccharidesIBA
12/2021
14- (N- methylamino)- 4'- (2- (2- (2- fluoroethoxy)ethoxy)ethoxy)stilbeneIBA
01/2021
1Cholinergic ReceptorsIBA
01/2021
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
01/2021
1Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
01/2020
1Interleukin-1 (Interleukin 1)IBA
01/2020
1InflammasomesIBA
01/2020
1Amyloid beta-PeptidesIBA
01/2020
1Ion Channels (Ion Channel)IBA
01/2018
1Peptides (Polypeptides)IBA
01/2018
1NeurograninIBA
07/2017
1C-Reactive ProteinIBA
08/2011
1LipidsIBA
08/2011
1indoleacetamideIBA
03/2011
1SSR180575IBA
03/2011
1N,N- diethyl- 2- (2- (4- methoxyphenyl)- 5,7- dimethyl- pyrazolo(1,5- a)pyrimidin- 3- yl)- acetamideIBA
04/2007

Therapy/Procedure

2Therapeutics
01/2017 - 12/2008